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Genexys BioMed Awarded $320K SBIR Grant to Advance Novel Cystic Fibrosis Gene Therapy

NIH Grant to Accelerate Development of Innovative Non-Viral, Non-Lipid Platform Originating from Cincinnati Children's

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Publication

Long-term transgene expression in the central nervous system using DNA nanoparticles

This study demonstrates proof of concept for delivery and expression of compacted plasmid DNA in the central nervous system.

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Publication

DNA nanoparticles: detection of long-term transgene activity in brain using bioluminescence imaging

In this study, we used bioluminescence imaging (BLI) to track long-term transgene activity following the transfection of brain cells using a nonviral gene therapy technique.

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Publication

Bioluminescent imaging of reporter gene expression in the lungs of wildtype and model mice following the administration of PEG-stabilized DNA nanoparticles

DNA nanoparticles (DNPs) formed by compacting DNA with polyethyleneglycolylated poly-L-lysine are a nonviral vector shown to be safe and efficacious in animals and humans.

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